Jian Fang Selected Research

1- (1- (imidazo(1,2- a)pyridin- 6- yl)ethyl)- 6- (1- methyl- 1H- pyrazol- 4- yl)- 1H- (1,2,3)triazolo(4,5- b)pyrazine

10/2021	Once-daily savolitinib in Chinese patients with pulmonary sarcomatoid carcinomas and other non-small-cell lung cancers harbouring MET exon 14 skipping alterations: a multicentre, single-arm, open-label, phase 2 study.
1/2021	A phase Ib study of the highly selective MET-TKI savolitinib plus gefitinib in patients with EGFR-mutated, MET-amplified advanced non-small-cell lung cancer.
1/2019	Response and acquired resistance to savolitinib in a patient with pulmonary sarcomatoid carcinoma harboring MET exon 14 skipping mutation: a case report.

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Jian Fang Research Topics

Disease

38	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2022 - 06/2006
37	Neoplasms (Cancer) 10/2022 - 12/2002
14	Disease Progression 10/2022 - 01/2019
14	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2006
12	Lung Neoplasms (Lung Cancer) 01/2022 - 11/2004
9	Stomach Neoplasms (Stomach Cancer) 01/2021 - 01/2017
7	Adenocarcinoma of Lung 07/2021 - 04/2013
7	Infections 01/2018 - 01/2015
6	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2022 - 05/2015
6	Hypertension (High Blood Pressure) 07/2021 - 05/2009
5	Exanthema (Rash) 01/2022 - 11/2010
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2022 - 09/2006
5	Inflammation (Inflammations) 12/2021 - 10/2011
5	Nausea 01/2021 - 11/2004
5	Brain Neoplasms (Brain Tumor) 01/2020 - 12/2006
4	Carcinoma (Carcinomatosis) 10/2021 - 01/2018
4	Vomiting 01/2021 - 11/2004
4	Fibrosis (Cirrhosis) 01/2017 - 12/2010
3	Hepatocellular Carcinoma (Hepatoma) 08/2022 - 02/2020
3	Atherosclerosis 07/2021 - 01/2018
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 01/2018
3	Liver Neoplasms (Liver Cancer) 05/2020 - 08/2019
3	Wounds and Injuries (Trauma) 01/2016 - 05/2006
3	Adenocarcinoma 04/2013 - 06/2006
2	Colitis 04/2022 - 01/2019
2	Bone Resorption 04/2022 - 01/2019
2	Diarrhea 01/2022 - 01/2022
2	Proteinuria 07/2021 - 12/2018
2	Virus Diseases (Viral Diseases) 10/2020 - 02/2015
2	Multiple Myeloma 04/2019 - 12/2017
2	Breast Neoplasms (Breast Cancer) 01/2019 - 11/2004
2	B-Cell Lymphoma (Lymphoma, B Cell) 10/2018 - 10/2017
2	Seizures (Absence Seizure) 01/2018 - 11/2017
2	Hypoxia (Hypoxemia) 10/2017 - 06/2017
2	Pain (Aches) 05/2014 - 10/2011
2	Fatigue 04/2013 - 11/2004

Drug/Important Bio-Agent (IBA)

10	Tyrosine Kinase InhibitorsIBA 10/2022 - 06/2006
9	Proteins (Proteins, Gene)FDA Link 04/2022 - 09/2006
9	PlatinumIBA 07/2021 - 10/2012
8	Messenger RNA (mRNA)IBA 04/2022 - 09/2006
8	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2017
8	Pharmaceutical PreparationsIBA 01/2022 - 08/2019
8	ErbB Receptors (EGF Receptor)IBA 01/2022 - 06/2006
7	Cisplatin (Platino)FDA LinkGeneric 01/2019 - 11/2004
6	Bevacizumab (Avastin)FDA Link 07/2021 - 12/2019
5	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 11/2004
5	Long Noncoding RNAIBA 01/2020 - 12/2015
5	Gemcitabine FDA Link 01/2019 - 11/2004
4	Immune Checkpoint InhibitorsIBA 06/2022 - 01/2021
4	Gefitinib (Iressa)FDA Link 01/2022 - 06/2006
4	Pemetrexed (MTA)FDA Link 02/2021 - 10/2012
4	Carboplatin (JM8)FDA LinkGeneric 01/2021 - 11/2004
4	Biological ProductsIBA 01/2020 - 09/2017
3	CrizotinibIBA 06/2022 - 05/2016
3	Glucose (Dextrose)FDA LinkGeneric 04/2022 - 01/2019
3	camrelizumabIBA 01/2022 - 01/2021
3	RNA (Ribonucleic Acid)IBA 12/2021 - 10/2014
3	1- (1- (imidazo(1,2- a)pyridin- 6- yl)ethyl)- 6- (1- methyl- 1H- pyrazol- 4- yl)- 1H- (1,2,3)triazolo(4,5- b)pyrazineIBA 10/2021 - 01/2019
3	CholesterolIBA 07/2021 - 01/2016
3	Circulating Tumor DNAIBA 01/2021 - 01/2018
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2019 - 09/2014
3	Small Interfering RNA (siRNA)IBA 04/2019 - 02/2017
3	Interleukin-6 (Interleukin 6)IBA 01/2019 - 04/2016
3	tanshinoneIBA 10/2018 - 12/2010
2	Anaplastic Lymphoma KinaseIBA 06/2022 - 01/2019
2	B7-H1 AntigenIBA 06/2022 - 01/2021
2	Tartrate-Resistant Acid PhosphataseIBA 04/2022 - 05/2019
2	Phosphotransferases (Kinase)IBA 04/2022 - 10/2017
2	LigandsIBA 01/2022 - 07/2015
2	aumolertinibIBA 01/2022 - 01/2022
2	Monoclonal AntibodiesIBA 01/2022 - 12/2019
2	EndostatinsIBA 07/2021 - 07/2016
2	Sirtuin 1IBA 03/2021 - 06/2017
2	CytokinesIBA 01/2021 - 12/2005
2	Emodin (Archin)IBA 01/2021 - 12/2005
2	PhytochemicalsIBA 01/2021 - 01/2018
2	ensartinibIBA 01/2021 - 01/2020
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2021 - 01/2020
2	Biosimilar PharmaceuticalsIBA 01/2021 - 12/2019
2	Circular RNAIBA 01/2021 - 01/2019
2	anlotinibIBA 12/2020 - 01/2019
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 10/2020 - 01/2018
2	Aprepitant (Emend)FDA Link 10/2020 - 06/2014
2	AntiemeticsIBA 10/2020 - 06/2014
2	CateninsIBA 02/2020 - 04/2019
2	Alanine Transaminase (SGPT)IBA 01/2020 - 04/2013
2	Hormones (Hormone)IBA 09/2019 - 01/2017
2	salicylhydroxamic acid (SHAM)IBA 05/2019 - 12/2005
2	Blood Glucose (Blood Sugar)IBA 01/2019 - 01/2016
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2016 - 12/2005
2	CollagenIBA 01/2013 - 12/2010

Therapy/Procedure

29	Drug Therapy (Chemotherapy) 01/2022 - 11/2004
26	Therapeutics 10/2022 - 01/2006
6	Radiotherapy 10/2020 - 12/2002
2	Neoadjuvant Therapy 01/2022 - 10/2020
2	Chemoradiotherapy 01/2022 - 10/2020
2	Immunotherapy 01/2021 - 10/2012
2	Length of Stay 01/2016 - 01/2015
2	Electroacupuncture 05/2014 - 06/2006
2	Surgical Instruments (Clip) 01/2013 - 07/2011